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KMID : 1123920100240050837
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Korean Journal of Oriental Physiology and Pathology
2010 Volume.24 No. 5 p.837 ~ p.842
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Study on the Antioxidative, Antiaging and Whitening Effects of Bathing Aid SP1 and SP2
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Jugn Bo-Kyoung
Park So-Jung
Kim Jung-Soo
Han Seung-Heon
Sohn Kyung-Woo
Yoon Mi-Young
Lee Sun-Kyung
Lee Sang-Jae
Kim Byung-Joo
Kwon Young-Kyu
Chae Han
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Abstract
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The purpose of this study is to develop bathing aids as a strategic products to promote the medical tourism in Sancheong Jirisan Oriental medicinal herbs special district using medicinal herbs produced in Sancheong province, and to verify the effect of the bathing aids in vitro. We investigated the cytotoxicity activity, antioxidant activity, antiaging and whitening effects of Sanchung-PNU 1 (SP1) and Sanchung-PNU 2 (SP2) made with traditional medicinal herbs. The cytotoxicity activity was measured by MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide) assay. Antioxidant activities were determined by DPPH (1.1-diphenyl-2-picrylhydrazyl) radical scavenging capacity assay. We measured the inhibitory effect against tyrosinase activity to prove the whitening effect, and the inhibitory effect against elastase activity to prove the anti-aging effect. Two proposed prescriptions, SP1 and SP2, showed not significant cytotoxicity but significant (p<0.001) improvement in anti-oxidation, anti-wrinkle, and whitening effects compared to the control group. The result shows that these bathing aids have excellent DPPH radical scavenging effect and significant inhibitory effect against elastase and tyrosinase activity. These findings suggest that these bathing aids have a strong antioxidant, anti-aging, and whitening effect.
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KEYWORD
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traditional Korean Medicinal herb, bathing aids, antioxidation, anti-wrinkle, whitening, Sancheong
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